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MEG/EEG

PET

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MEG/EEG

PET

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Publications

 

MEG / EEG

Journal Papers:

  1. E. Kucukaltun-Yildirim, D. Pantazis and RM Leahy, Task-Based Comparison of Inverse Methods in MEG, IEEE Trans. Biomed. Eng., 53(9):1783-1793, 12, 2006 link

  2. F. Darvas, J.J. Ermer, J.C. Mosher, R.M. Leahy, Generic head models for atlas-based EEG source analysis, Human Brain Mapping, 27 (2): 129-143, 2006 link

  3. A. Ossadtchi, J.C. Mosher, W.W. Sutherling, R. Greenblatt, R.M. Leahy, Hidden Markov modelling of spike propagation from interictal MEG data, Phys. Med. Bio, 50 (14): 3447-3469, 2005 pdf

  4. D. Pantazis, T. E Nichols, S. Baillet, RM Leahy, A Comparison of Random Field Theory and Permutation Methods for the Statistical Analysis of MEG data, Neuroimage, 25(2):383-394, 2005. link


  5. F. Darvas, M. Rautiainen, D. Pantazis, H. Benali, S. Baillet, JC Mosher, L. Garnero, RM Leahy, Investigations of Dipole Localization Accuracy in MEG using the Bootstrap, Neuroimage, 25(2):355-368, 2005 link


  6. F. Darvas, D. Pantazis, E. Kucukaltun-Yildirim and R.M. Leahy, "Mapping human brain function with MEG and EEG: methods and validation ", Neuroimage, 23(supplement 1): S289-S299, 2004. pdf

  7. K. Jerbi, S. Baillet, J.C. Mosher, G. Nolte, L. Garnero, R.M. Leahy, "Localization of Realistic Cortical Activity in MEG using Current Multipoles", Neuroimage, 22(2): 779-793, June 2004. pdf

  8. A. Ossadtchi, S. Baillet, J.C. Mosher, D. Thyerlei, W. Sutherling, R.M. Leahy, "Automated Interictal Spike Detection and Source Localization in Magnetoencephalography Using Independent Components Analysis and Spatio-temporal Clustering", Clinical Neurophysiology, vol. 115, pp. 508-522, 2004. pdf

  9. K. Jerbi, J.C. Mosher, S. Baillet, R.M. Leahy, "On MEG forward modeling using multipolar expansions", Phys. Med. Biol., 47(4): 523-555, Feb 21 2002. pdf

  10. M. Akhtari, W.S. Sutherling, A.N. Mamelak, J.C. Mosher, D. Arthur, S. Sands, P. Weiss, N. Lopez, M. DiMauro, E. Flynn, R.M. Leahy, "Dipole Localization of Human Induced Focal Afterdischarge Seizure in Simultaneous Magnetoencephalography and Electrocorticography", Brain Topography, 14(2): 101-116, 2001. pdf

  11. J.J. Ermer, J.C. Mosher, S. Baillet, R.M. Leahy, "Rapidly recomputable EEG forward models for realistic head shapes", Phys Med Biol, 46(4): 1265-1281, Apr. 2001. pdf

  12. S. Baillet, J.C. Mosher, R.M. Leahy, "Electromagnetic Brain Mapping", (invited article), IEEE Signal Processing Magazine, 18(6): 14-30, Nov 2001. pdf

  13. J.J. Ermer, J.C. Mosher, M.X. Huang, R.M. Leahy, Paired MEG data set source localization using recursively applied and projected (RAP) MUSIC, IEEE Transactions on Biomedical Engineering, 47(9): 1248-1260 Sep. 2000. pdf

  14. J.C. Mosher, S. Baillet, R.M. Leahy, "EEG Source Localization and Imaging Using Multiple Signal Classification Approaches", Journal of Clinical Neurophysiology, 16(3): 225-238, May 1999. [Review Article] pdf

  15. J.C. Mosher, R.M. Leahy, P.S. Lewis, "EEG and MEG: forward solutions for inverse methods", IEEE Transactions on Biomedical Engineering, 46(3): 245 -259, March 1999. pdf

  16. J.C. Mosher, R.M. Leahy, "Source localization using recursively applied and projected (RAP) MUSIC", IEEE Transactions on Signal Processing, 47(2), 332-340, Feb. 1999. pdf

  17. M.X. Huang, J.C. Mosher and R.M. Leahy, "A sensor-weighted overlapping-sphere head model and exhaustive head model comparison for MEG",Physics in Medicine and Biology, 44(2): 423-440, Feb. 1999. pdf

  18. J.C. Mosher, R.M. Leahy, "Recursive MUSIC: A framework for EEG and MEG source localization", IEEE Transactions on Biomedical Engineering, 45(11), 1342-1354, Nov. 1998. pdf

  19. R.M. Leahy, J.C. Mosher, M.E. Spencer, M.X. Huang, J.D. Lewine, "A study of dipole localization accuracy for MEG and EEG using a human skull phantom", Electroencephalography and Clinical Neurophysiology. 107(2): 159-173, Aug. 1998. pdf

  20. Weiss S, Leahy R.M., Mosher J.C., Stewart R., "An Ensemble De-Noising Method For Spatio-Temporal EEG/MEG data", Applied Signal Processing, Vol. 4, pp. 142-153, 1997 (issue actually published in 1998). pdf

  21. J.W. Phillips, R.M. Leahy, J.C. Mosher, B. Timsari, "Imaging neural activity using MEG and EEG", IEEE Engineering in Medicine and Biology Magazine(2nd Student Paper Award Winner at IEEE EMBS 1996), 16(3): 34-42, May-June 1997. pdf

  22. J.W. Phillips, R.M. Leahy, J.C. Mosher, "MEG-based imaging of focal neuronal current sources", IEEE Transactions on Medical Imaging, 16(3): 338-348, June 1997. pdf

  23. J. C. Mosher, R. M. Leahy and P. Lewis , "Multiple dipole modeling and localization from spatiotemporal MEG data", IEEE Trans. Biomed. Eng., 39(5): 541-557, June 1992. pdf

  24. J.C. Mosher, M. Spencer, R.M. Leahy, P. Lewis, "Error bounds for MEG and EEG source localization ", Electroencephalography and Clinical Neurophysiology, 86(5): 303-321, May 1993. pdf

Conference Publications:


  1. H.Hui, R.M Leahy, "Linearly constrained MEG beamformers for MVAR modeling of cortical interactions," Biomedical Imaging: Macro to Nano, 2006. 3rd IEEE International Symposium on , vol., no.pp. 237- 240, 6-9 April 2006. pdf

  2. J.C. Mosher, S. Baillet, F. Darvas, D. Pantazis , E.K. Yildirim, R.M. Leahy, “BrainStorm Electromagnetic Imaging Software”, 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart (NFSI 2005), Minnesota, May 12-15, 2005. pdf

  3. D. Pantazis, W. Merrifield, F. Darvas, W. Sutherling, R.M. Leahy, "Identification of the Language Dominant Hemisphere using MEG Cortical Imaging and Permutation Tests", WSEAS 2005 International Conference on Cellular and Molecular Biology, Biophysics and Bioengineering, July 15-17, Vouliagmeni, Athens, Greece pdf

  4. DS. Hahn , F Darvas, D Thyerlei, MJ McMahon, JDWeiland, RM Leahy, MS Humayun, Spatiotemporal analysis of visually evoked potentials in the cortex of a blind subject with a chronic intraocular retinal prosthesis, Investigative Ophthalmology and visual science 46: 1496 Suppl. S 2005 (abstract)

  5. K. Jerbi, S. Baillet, JP Lachaux, D. Pantazis, RM Leahy, L Garnero, Modulations of power and synchronization of neural activity during sustained visuomotor coordination: an MEG study, Human Brain Mapping Conference, Toronto, June 2005. (abstract).

  6. D. Pantazis , D.L. Weber, C.C. Dale, T.E. Nichols, G.V. Simpson, R.M. Leahy, "Imaging of oscillatory behavior in event-related MEG studies", Proceedings of SPIE, Computational Imaging III, Vol. 5674, C.A. Bouman, E.L. Miller (Eds), 2005 link


  7. J.C. Mosher, "A review on the Importance of Volume Currents", Biomag 2004, Boston, August 8-12, 2004 (powerpoint)


  8. D. Pantazis , C.C. Dale, D.L. Weber, T.E. Nichols, G.V. Simpson, R.M. Leahy, "Imaging and Detection of Oscillatory Activity in MEG using Time-Frequency Analysis and Permutation Tests", Proceedings Biomag 2004, Boston, August 8-12, 2004 (pdf)


  9. E.K. Yildirim, D. Pantazis , R.M. Leahy, "Objective Evaluation of Inverse Methods in MEG", Proceedings Biomag 2004, Boston, August 8-12, 2004 (pdf)


  10. J.C. Mosher, S. Baillet, R.M. Leahy, "Equivalence of Linear Approaches in
    Bioelectromagnetic Inverse Solutions," 2003 IEEE Workshop on Statistical
    Signal Processing, Sep 2003, St. Louis, Missouri, pp. 294-297. (pdf)

  11. K. Jerbi, S. Baillet, J.C. Mosher, L. Garnero, R.M. Leahy, "Modeling Realistic Patches of Cortical Activity with Current Multipoles", 4th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, Chieti, Italy, Sept. 10-13, 2003.

  12. D. Pantazis, T. Nichols, S. Baillet, R.M. Leahy, "Spatiotemporal Localization Of Significant Activation In MEG Using Permutation Tests", I Taylor, C., Noble, J. A. (Eds), Proc. 18th Conf. Information Processing in Medical Imaging. pp. 512-523, July 2003.

  13. F. Darvas, M. Rautiainenm, S. Baillet, A. Ossadtchi, J.C. Mosher, R. M Leahy, "Investigations of Dipole Localization Accuracy in MEG using the Bootstrap", ISBET, Santa Fe 2003. pdf

  14. F. Darvas, J.C. Mosher, R.M. Leahy, "Generic Head Models for Atlas-Based EEG-Source Analysis", Human Brain Mapping, New York 2003. doc

  15. A. Ossadtchi, J.C. Mosher, S. Baillet, N. Lopez, W.S. Sutherling, R. M. Leahy, "Automated Detection of Dipole Clusters in Interictal MEG Data", 13th International Conference on Biomagnetism, August 8-14 2002, Jena, Germany

  16. K. Jerbi, J.C. Mosher, G. Nolte, S. Baillet, L. Garnero, R.M. Leahy, "From Dipoles to Multipoles: Parametric Solutions to the Inverse Problem in MEG", 13th International Conference on Biomagnetism, August 8-14 2002, Jena, Germany. pdf

  17. S. Baillet, C. Adam, D. Schwartz, R.M. Leahy, J.C. Mosher, B. Renault, M. Baulac, L. Garnero, "Combined MEG and EEG Source Imaging of Interictal Activity in Partial Epilepsy", 13th International Conference on Biomagnetism, August 8-14 2002, Jena, Germany, in press.

  18. A. Ossadtchi, R.M. Leahy, J.C. Mosher, N. Lopez, W. Sutherling, "Automated Interictal Spike Detection and Source Localization in MEG Using ICA and Spatial-Temporal Clustering ", 2002 IEEE International Symposium on Biomedical Imaging Macro to Nano, June 2002.

  19. W.S. Sutherling, M. Akhtari, A.N. Mamelak, J.C. Mosher, D. Arthur, S. Sands, P. Weiss, N. Lopez, M. DiMauro, E. Flynn, R.M. Leahy, "Dipole Localization of Human Induced Focal Afterdischarge Seizure in Simultaneous Magnetoencephalography and Electrocorticography", Brain Topography, 14(2): 101-116, 2001. pdf

  20. A. Ossadtchi, J.C. Mosher, K. Jerbi, N. Lopez, S. Baillet, W.S. Sutherling, R.M. Leahy, "Automated Interictal Spike Detection & Source Localization in MEG using Independent Component Analysis", Proceedings of the Annual Meeting of the American Epilepsy Society, Epilepsia, Vol.42, Sup. 7, p. 73, Nov. 2001. (abstract only).

  21. S. Baillet, L. Gavit, C. Adam, D. Schwartz, A. Ducorps, J. Pescatore, R.M. Leahy, J.C. Mosher, L. Garnero, M. Baulac, "Combined High-Resolution MEG and EEG Source Imaging of Interictal Activity in Partial Epilepsy", Proceedings of the Annual Meeting of the American Epilepsy Society, Epilepsia, Vol.42, Sup. 7, p. 73, Nov 2001 (abstract only).

  22. K. Jerbi, R.M. Leahy, J.C. Mosher, S. Baillet, "Modeling extended sources in MEG using multipoles", Biomedizinische Technik, Band 46, Erganzungsband 2, 2001.

  23. J.J. Ermer, S. Baillet, J.C. Mosher, R.M. Leahy, "Rapidly re-computable EEG forward models for realistic head shapes", Proceedings Biomag 2000, Helsinki, Aug 2000.

  24. A. Ossadtchi, S. Baillet, J.C. Mosher, R.M. Leahy, "Using mutual information to select event-related components in ICA", Proceedings Biomag 2000, Helsinki, Aug 2000.

  25. S. Baillet, J.C. Mosher, K. Jerbi, R.M. Leahy, "Hybrid MEG source characterization by cortical remapping and imaging of parametric source models", Proceedings Biomag 2000, Helsinki, Aug 2000.

  26. K. Jerbi. S. Baillet, J.C. Mosher, R.M. Leahy, "Error bound in MEG multipole localization", Proceedings Biomag 2000, Helsinki, Aug 2000.

  27. J.C. Mosher, S. Baillet, K. Jerbi, R.M. Leahy, "MEG Multipolar Modeling of Distributed Sources Using RAP MUSIC", IEEE Proc. 34th Asilomar Conf. on Signals, Systems, and Computers, Pacific Grove, CA, Vol.1, pp 318-322, Nov 2000. pdf

  28. J. C. Mosher, R. M. Leahy, D. W. Shattuck, S. Baillet, "MEG Source Imaging using Multipolar Expansions", Proceedings of the 16th Conference on Information Processing in Medical Imaging, IPMI'99, Visegrád, Hungary, June/July 1999, Springer Series in Computer Science, pp.15-28, A. Kuba, M. Sámal, A. Todd-Pokropek (Eds.): June/July 1999. pdf

  29. J.C. Mosher, R.M. Leahy, M. Huang, M.E. Spencer, "Modeling versus Accuracy in EEG and MEG data", NFSI '97 in Biomedizinische Technik, Vol 42, No. 1, pp. 5-8, 1997. pdf

  30. J. Phillips, R.M. Leahy, J.C. Mosher, "Dynamic Bayesian imaging using the magnetoencephalogram", Proceedings, IEEE Engineering in Medicine and Biology 18th Annual International Conference, (Second Place in Whitaker Foundation International Student Paper Competition) 817-818, 1996. pdf

  31. J. Phillips, R.M. Leahy and J.C. Mosher, "Dynamic MEG Imaging of Focal Neuronal Sources", Proceedings, IEEE Nuclear Science Symposium and Medical Imaging Conference, Anaheim, CA, pp 1928-1932, Nov. 1996. pdf

  32. J.C. Mosher, R.M. Leahy, P. Lewis, "Matrix kernels for MEG and EEG source localization and imaging ", Invited Paper, Proc. IEEE Int. Conf. Acoust. Speech and Signal Proc., Detroit, April, 1995. ICASSP-95., Volume: 5, pp. 2943-2946, 1995. pdf

  33. P. Lewis, J.C. Mosher, R.M. Leahy, "Neuromagnetic source reconstruction ", Invited Paper, Proc. IEEE Int. Conf. Acoust. Speech and Signal Proc., Detroit, April, 1995, Volume: 5, pp. 2911-2914, 1995. pdf

  34. J.C. Mosher, R.M. Leahy, P. Lewis, "Biomagnetic localization from transient quasi-static events ", Proc. IEEE Int. Conf. Acoust. Speech and Signal Proc., Volume 1, pp. 91-94, Minneapolis, April 1993. pdf

  35. Spencer MS, Leahy RM, Mosher JC, Lewis PS, “Adaptive filters for
    monitoring localized brain activity,” IEEE Proc. 26th Asilomar Conf. on
    Signals, Systems, and Computers, Pacific Grove, CA, October 1992, pp
    156–160. pdf

PET

Journal Papers:


  1. S Cho, Q Li, S Ahn, B. Bai, RM Leahy, Iterative Image Reconstruction using Inverse Fourier Rebinning for Fully 3D PET, IEEE Trans. Med. Imag., IEEE Trans. Med. Imag, 26 (3):347-358, 2007 link

  2. Q Li, E Asma, S Ahn, RM Leahy, A Fast Fully 4D Incremental Gradient Reconstruction Algorithm for List Mode PET Data, IEEE Trans. Med. Imag, 26 (1):58-67, 2007 link

  3. Q Li, RM Leahy, Statistical modeling and reconstruction of randoms precorrected PET data, IEEE Trans. Med. Imag, 25(12): 1565-1572, 2006 link

  4. J. Qi and RM Leahy, Iterative reconstruction techniques in emission computed tomography, Phys. Med. Biol. (invited topical review), 51:R541-R578, 2006 link

  5. A. Ruangma, B. Bai, J.S. Lewis, X. Sun, MJ Welch, RM Leahy, R. Laforest, Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides, Nucl. Med. Biol., 33(2):217-226, 2006. link

  6. E. Asma and R.M. Leahy, Mean and covariance properties of dynamic PET data reconstructions from list-mode data, IEEE Trans. Med. Imag., 25(1):42 - 54, 2006 pdf

  7. Q. Li, E. Asma, J. Qi, R.M. Leahy, "Accurate Estimation of the Fisher Information Matrix for the PET Image Reconstruction Problem", to appear: IEEE Trans. Med. Imag., 2004. pdf

  8. Y. Yang, Y.C. Tai, S. Siegel, D. Newport, B. Bai, Q. Li, R.M. Leahy and S.R. Cherry, "Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging", Phys. Med. Biol, Phys. Med. Biol. Vol. 49, 2527-2545, 2004. pdf

  9. E. Asma, D.W. Shattuck, R.M. Leahy, "Losses Compression of Dynamic PET Data", IEEE Transactions on Nuclear Science, 50 (1): 9-16, Feb.2003. pdf

  10. B. Bai, Q. Li, C. H. Holdsworth, E. Asma, Y. C. Tai, A. Chatziioannou and R. M. Leahy, " Model-based normalization for iterative 3D PET image reconstruction ", Physics in Medicine and Biology, 47: 2773-2784 (2002). pdf

  11. Berger F., Lee Y.P., Loening A.M., Chatziioannou A., Freedland S.J., Leahy R.M., Lieberman J.R., Belldegrun A.S., Sawyers C.L., Gambhir S.S., "Whole-body skeletal imaging in mice utilizing microPET: Optimization of Reproducibility and Applications in Animal Models of Bone Disease", Euro. J. Nucl. Med and Mol. Imag, 29 (9): 1225-1236, SEP 2002. abstract

  12. D.W. Shattuck, J. Rapela, E. Asma, A. Chatzioannou, J. Qi and R.M. Leahy, "Internet2-based 3D PET image reconstruction using a PC cluster ", Physics in Medicine and Biology, 47: 2785-2795, 2002. pdf

  13. T.E. Nichols, J. Qi, E. Asma, R.M. Leahy, "Spatiotemporal Reconstruction of List Mode PET Data ", IEEE Transactions on Medical Imaging, 21(4):396-404 April 2002. pdf

  14. P. Bonetto, J. Qi, R.M Leahy, "Covariance approximation for fast and accurate Computation of Channelized Hotelling Observer Statistics", IEEE Transactions on Nuclear Science, 47 (4) 1567-1572 Part 2 Aug 2000. pdf

  15. A. Chatziioannou, A. Moore, A. Annala, K. Nguyen, R.M. Leahy, S. Cherry, "Comparison of 3D MAP and filtered backprojection algorithms for high resolution animal imaging with microPET", IEEE Trans. Medical Imaging, Vol. 19, pp. 507-512, May 2000. pdf

  16. J. Qi and R.M. Leahy, "Resolution and noise properties of MAP reconstructions in fully 3D PET", IEEE Trans. Medical Imaging, Vol 19(5), pp. 493-506, May 2000. pdf

  17. J. Qi and R.M. Leahy, "A theoretical study of the contrast recovery and variance of MAP reconstructions from PET data", IEEE Trans. Med. Imag., Vol. 18, Issue:4, pp. 293-305, April 1999. pdf

  18. J. Qi, R.M. Leahy, C. Hsu, T. Farquhar, S. Cherry, "Fully 3D Bayesian image reconstruction for the ECAT EXACT HR+ ", IEEE Trans. Nucl. Sci., Vol. 45(3): 1096-1103, Part 2, June 1998. pdf

  19. J. Qi, R. M. Leahy, S. R. Cherry, A. Chatziioannou and T. H. Farquhar, "High resolution 3D Bayesian image reconstruction using the microPET small-animal scanner", Physics in Medicine and Biology, 43(4): 1001-1013, Apr. 1998. pdf

  20. M. Chan, R. Leahy, E Mumcuoglu, S. Cherry, "Comparing lesion detection performances of PET image reconstruction algorithms: a case study", IEEE Trans. Nuclear Science, 44(4): 1558-1563, August 1997. pdf

  21. Z. Zhou, R.M. Leahy and J. Qi, "Approximate Maximum likelihood hyperparameter estimation for Gibbs priors", IEEE Trans. Image Processing, 6(6): 844-861, June 1997. pdf

  22. E. Mumcuoglu, R.M. Leahy and S. Cherry, "Bayesian Reconstruction Of PET Images: quantitative methodology and performance analysis", Physics in medicine and Biology, 41(9):1777-1807 Sep 1996. link

  23. E. Mumcuoglu, R.M. Leahy, S. Cherry and Z. Zhou, "Fast gradient based methods for Bayesian reconstruction of transmission and emission PET images", IEEE Trans. Medical Imaging, 13(4): 687-701, Dec. 1994. pdf

  24. T. Hebert and R.M. Leahy, "Statistic-based 3D MAP image reconstruction from Poisson data using Gibbs priors", IEEE Trans. Signal Processing, Vol. 40, pp 2290-2303, 1992. pdf

  25. M. Singh, R.M. Leahy, K. Oshio, R. Brechner and X. Yan, "A new generation of SPECT and PET systems based photomultipliers", IEEE Trans. Nucl. Sci., vol. NS-37, 1321-1327, 1990. pdf

  26. M. Singh, R. Leahy, R. Brechner and X. Yan, "Design and imaging studies of a position sensitive photomultiplier based dynamic SPECT system", IEEE Trans. Nucl. Sci.,36 (1): 1132-1137 Part 1 1989. pdf

  27. T. Hebert, R.M. Leahy and M. Singh, "3D Maximum-Likelihood reconstruction for an electronically collimated single-photon-emission imaging-system", J. Opt Soc Ama 7(7): 1305-1313 July 1990. pdf

  28. T. Hebert and R.M. Leahy, "A generalized EM algorithm for 3D Bayesian reconstruction from Poisson data using Gibbs distributions", IEEE Trans. Med. Imag., Vol. 8, pp 194-202, 1989. pdf

  29. M. Singh, R.M. Leahy, R. Brechner and T. Hebert, "Noise propagation in electronically collimated single photon imaging", IEEE Trans. Nucl. Sci., 35(1): 772-777, Part 1 Feb 1988. pdf

  30. T. Hebert, R.M. Leahy and M. Singh, "Fast MLE for SPECT using an intermediate polar representation and a stopping criterion", IEEE Trans. Nucl. Sci.,35(1) 615-619 Part 1 Feb 1988. pdf

  31. R. Brechner, M. Singh and R.M. Leahy, "Computer simulation studies of tomographic reconstruction with an electronically collimated camera for SPECT", IEEE Trans. Nucl. Sci.,34(1): 369-373 Feb 1987.

  32. R.M. Leahy and J. Qi, "Statistical approaches in quantitative positron emission tomography", invited review article, Statistics and Computing, Vol. 10, pp 147-165, 2000. pdf

Conference Publications:


  1. E. Asma and RM. Leahy, Accurate Dynamic FIM Estimation from List-Mode PET Data for Uniform Resolution Reconstructions, Conf. Record: IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Puerto Rico, pp 1822-26, 2005. pdf

  2. Q. Li, S Ahn and RM Leahy, Fast Hybrid Algorithms for PET Image Reconstruction, Conf. Record: IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Puerto Rico, pp 1851-55, 2005. pdf

  3. S Cho, Q Li, SAhn and RM. Leahy, Fast Projectors for Iterative 3D PET Reconstruction, Conf. Record: IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Puerto Rico, pp 1933-37, 2005. pdf

  4. B.Bai, R. Laforest, A M. Smith and RM. Leahy, Evaluation of MAP Image Reconstruction with Positron Range Modeling for 3D PET, Conf. Record: IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Puerto Rico, pp 2686-89, 2005. pdf

  5. S Somayajula, E Asma, and RM. Leahy, PET Image Reconstruction using Anatomical Information through Mutual Information Based Priors, Conf. Record: IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Puerto Rico, pp 2722-26, 2005. pdf

  6. B. Bai, A. M. Smith, D. F. Newport, R. M. Leahy , On the Effect of Modeling Block Detector Structure in Small Animal PET Scanners, IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Rome, Oct, 2004 (abstract)

  7. E. Asma, R. M. Leahy , Theoretical Comparison of Uniform Resolution Penalized Likelihood Dynamic PET Images with Multiframe Penalized Likelihood Static PET Images, IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Rome, Oct, 2004 (abstract)

  8. Q. Li, E. Asma, R. M. Leahy, Fully 4D Dynamic PET Image Reconstruction from microPET R4 List Mode Data, IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Rome, Oct, 2004 (abstract)

  9. A. Ruangma, R. Laforest, B. Bai, R. M. Leahy, Characterization of USC-MAP Image Reconstruction on Micropet-R4, IEEE Nucl. Sci. Symp. Med. Imag. Conf. , Rome, Oct, 2004 (abstract)

  10. Q. Li, E. Asma, R.M. Leahy, "A Fast Fully 4D Incremental Gradient Reconstruction Algorithm for List Mode PET Data", Proceedings IEEE Int. Symp. Biomed. Imag., April 2004. pdf

  11. Q. Li, E. Asma, J. Qi, J.R. Bading, R.M. Leahy, "Accurate Estimation of the Fisher Information Matrix for the PET Image Reconstruction Problem", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, OR, 2003. pdf

  12. B. Bai, A. Ruangma, R. Laforest, Y.C. Tai, R.M. Leahy, "Positron Range Modeling for Statistical PET Image Reconstruction", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, OR, 2003. pdf

  13. R. Laforest, A. Ruangma, J.S. Lewis, X. Sun, M.J. Welch, B. Bai, R.M. Leahy, "MicroPet Imaging Of Radiopharmaceuticals Labeled With Three Copper Radionuclides", Int. Symposium for RadioPharmaceutical Chemistry, Sydney, Australia (abstract only) Aug 2003.

  14. A. Ruangma, R. Laforest, J.S. Lewis, X. Sun, Y. Tai, M.J. Welch, B. Bai, R.M. Leahy, "Initial Evaluation Of Usc-Map From The Imaging Of Radiopharmaceuticals Labeled With Three Copper Radionuclides", Academy of Molecular Imaging, Madrid, Spain (abstract only) Sept. 2003.

  15. Y. Yang, Y.C. Tai, B. Bai, A. Chatziioannou, R. Silverman, K. Meadors, S. Siegel, D. Newport, Q. Li, R.M. Leahy, S. Cherry, "Performance Measurements on the microPET II Small Animal Scanner", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, 2003, Portland, OR, 2003.

  16. E. Asma, T.E. Nichols, R.M. Leahy, "Temporally Invariant Uniform Spatial Resolution in Dynamic PET", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, OR, 2003. pdf

  17. B. Bai, P. Chow, A. Chatziioannou, R. M. Leahy, "Fully 3D Uniform Resolution Transmission PET Image Reconstruction", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Norfolk, 2002. pdf

  18. E. Asma, T.E. Nichols and R.M. Leahy, "Temporal Resolution Properties of Dynamic PET Images", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Norfolk, 2002. pdf

  19. R.M. Leahy, B. Bai, E. Asma, Q. Li, D.W. Shattuck, "MAP Image Reconstruction Software Concorde MicroPET Scanners", Academy of Molecular Imaging, Oct, 2002, San Diego

  20. E. Asma, D.W. Shattuck, RM Leahy, "Lossless Compression of List-mode 3DPET Data", Nuclear Science Symposium Conference Record, 2001 IEEE, Vol. 2, pp.4-10, Nov 2001. pdf

  21. E. Asma, T.E. Nichols, J. Qi, R.M. Leahy, "4D PET Image Reconstruction from List Mode Data", in Conference record, IEEE Int. Nucl. Sci. Symp. and Medical Imaging Conf., Lyons, Oct., 2000. pdf

  22. T. Nichols, J. Qi, and R.M. Leahy,"Continuous Time Dynamic PET Imaging Using List Mode Data", Proc. 1999 Int. Conf. on Information Processing in Medical Imaging, IPMI99, Springer Verlag, Lecture Notes in Computer Science Eds. A. Kuba et al., pp.98-111, 1999. pdf

  23. E. Mumcuoglu, R.M. Leahy, S. Cherry, E. Hoffman, "Accurate Geometric and Physical Response Modeling for Statistical Image Reconstruction in High Resolution PET Scanners", IEEE Nuclear Science Symposium and Medical Imaging Conference, Anaheim, CA, pp. 1569-1573, Nov. 1996. pdf

  24. E. Mumcuoglu, R.M. Leahy, Z. Zhou, S. Cherry, "A phantom study of the quantitative behavior of Bayesian PET reconstruction methods ", Proc. IEEE Medical Imaging Conference, Volume: 3, pp. 1703-1707, 1995. pdf

  25. Z. Zhou, R.M. Leahy, E. U. Mumcuoglu, "Simultaneous hyperparameter estimation and Bayesian image reconstruction for PET ", Proc. IEEE Nuclear Sci. Symp. and Medical Imaging Conf., 1994., Volume: 4, pp. 1604-1608, 1995. pdf

Image Analysis

Journal Papers:


  1. A. Joshi, D.W. Shattuck, P.M. Thompson, R.M. Leahy, Simultaneous Surface and Volumetric Brain Registration Using Harmonic Mappings, IEEE Trans. Med. Imag, submitted

  2. B. Dogdas, D. Stout, A. Chatziioannou, RM Leahy, Digimouse: A 3D Whole Body Mouse Atlas from CT and Cryosection Data, Phys. Med. Bio., 52 (3):577-587, 2007 link

  3. C. Fennema-Notestine, B. Ozyurt, C.P. Clark., S. Morris. A. Bischoff-Grethe, M.W. Bondi, T.L. Jernigan, B. Fischl, F. Segonne, D.W. Shattuck, R.M. Leahy, D.E. Rex, A.W. Toga, K.H. Zou, G. G. Brown, Quantitative Evaluation of Automated Skull-Stripping Methods Applied to Contemporary and Legacy Images: Effects of Diagnosis, Bias Correction, and Slice Location, Human Brain Mapping, 27 (2): 99-113 FEB 2006. link

  4. B. Dogdas, D. Shattuck, RM Leahy, Segmentation of Skull and Scalp in 3D Human MRI Using Mathematical Morphology, Human Brain Mapping, 26(4):273-285, 2005. link

  5. D.W. Shattuck, R.M. Leahy, "Brain Suite: A Cortical Surface Identification Tool", (invited article), Medical Image Analysis, 6 (2): 129-142 Jun 2002. link

  6. J.B. Arnold, J-S. Liow, K.A. Schaper, J.J. Stern, J.G. Sled, D.W. Shattuck, A.J. Worth, M.S. Cohen, R.M. Leahy, J.C. Mazziotta, and D.A. Rottenberg, "Qualitative and Quantitative Evaluation of Six Bias-Correction Algorithms", NeuroImage, Vol. 13, No. 5, pp. 931-943, May 2001. link

  7. D.W. Shattuck, S.R. Sandor-Leahy, K.A. Schaper, D.A. Rottenberg, and R.M. Leahy, "Magnetic Resonance Image Tissue Classification Using a Partial Volume Model", NeuroImage, Vol. 13, No. 5, pp. 856-876, May 2001. pdf

  8. D.W. Shattuck and R.M. Leahy "Automated Graph Based Analysis and Correction of Cortical Volume Topology", IEEE Transactions on Medical Imaging, 20(11):1167-1177, November 2001. pdf

  9. S. Sandor and R. Leahy, "Surface based labelling of cortical anatomy using a deformable atlas", IEEE Transactions on Medical Imaging Vol 16(1), pp 41-54, Feb 1997. pdf

  10. Z. Wu and R.M. Leahy, "An Optimal Graph Theoretic Approach To Data Clustering: Theory And Its Application To Image Segmentation", IEEE Trans. on Pattern Analysis and Machine Intelligence, Vol. 15(11): 1101-1113 Nov 1993. pdf

Conference Publications:


  1. AA Joshi, DW Shattuck, PM Thompson, RM Leahy, A framework for registration, statistical characterization and classification of cortically constrained functional imaging data, Int. Conf. Info. Proc. Med. Imag. (IPMI), Springer Verlag Lecture Notes in Computer Science Vol. 3565: 186-196, 2005 (winner: best poster presentation at IPMI’05). link

  2. A. Joshi, D. Shattuck, PM. Thompson, RM Leahy, Thin Plate Spline Registration in the Intrinsic Geometry of the Cortical Surface, Human Brain Mapping Conference, Toronto, June 2005. (abstract).

  3. DW Shattuck, A Joshi, RM Leahy, AW Toga, Automated Cortical Surface Models from MRI, Human Brain Mapping Conference, Toronto, June 2005. (abstract).

  4. AA. Joshi, RM. Leahy, PM. Thompson, DW. Shattuck: Cortical Surface Parameterization by P-Harmonic Energy Minimization. Proc. IEEE International Symposium of Biomedical Imaging, April 2004. pdf

  5. R.M. Leahy, "3D Mouse atlas and cross-modality registration", 2nd Annual Meeting SMI, San Francisco (abstract only) 2003.

  6. D.W. Shattuck, D.E. Rex, F. Darvas, R.M. Leahy, A.W. Toga, "J Doe, Anonymizing MRI Data for the Protection of Research Subject Confidentiality", Human Brain Mapping, New York (abstract only) 2003.

  7. B. Dogdas, D.W. Shattuck, R.M. Leahy, "Segmentation of Patient Specific MEG/EEG Skull, Scalp, and Brain Models from MRI", Proceedings of Biomag 2002 Conference, August 2002. pdf

  8. B. Dogdas, D.W. Shattuck, R.M. Leahy, " Segmentation of the skull in 3D human MR images using mathematical morphology", Proceedings of SPIE Medical Imaging Conference, vol. 4684, paper 180, pp. 1553-1562, 2002. pdf

  9. D.W. Shattuck and R.M. Leahy, "Topologically constrained cortical surfaces from MRI," in Medical Imaging 2000: Image Processing, K. M. Hanson, Editor, Proc. of the SPIE Volume 3979, p. 747-758.

  10. D.W. Shattuck and R.M. Leahy,"BrainSuite: An Automated CorticalSurface Identification Tool", in S.L. Delp, A.M. DiGoia, and B. Jaramaz,(Eds.), Medical Image Computing and Computer-Assisted Intervention MICCAI 2000, Lecture Notes in Computer Science, pp. 51-61, Springer-Verlag, Berlin Heidelberg, 2000.

  11. D.W. Shattuck and R.M. Leahy, "Topological refinement of volumetric data," Medical Imaging 1999: Image Processing, K. M. Hanson, Editor, Proc. of the SPIE Volume 3661, p. 204-213.

Misc topics

Journal Papers:


  1. G. Zavattini, S. Vecchi, R.M. Leahy, BJ Pichler, D.J. Smith, S.R. Cherry, A hyperspectral fluorescence system for 3-D in vivo optical imaging, Phys. Med. Bio, 51: 2029-2043, 2006. link

  2. AJ Chaudhari, F Darvas, JR Bading, RA Moats, PS Conti, DJ Smith, SR Cherry and RM Leahy, Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging, Phys. Med. Bio, 50(23):5421-5442, 2005. link

  3. R.P. Singh, V.M. Brown, A. Chaudhari, R.M. Leahy, "High-Resolution Voxelation Mapping of Human and Rodent Brain Gene Expression", J. Neurosci Meth 125(1-2): 93-101 May, 2003. link

  4. A.H. Khan, A. Ossadtchi, R.M. Leahy, "Error-correcting Microarray Design", Genomics 81(2): 157-165 IEEE, 2003. abstract

  5. T.A. Lei, A. Ossadtchi, T.E. Nichols, R.M. Leahy, "Genes Regulated by Learning in the Hippocampus", J Neurisci Res 71(6): 763-768, Mar 2003. link

  6. A. Ossadtchi, V.M. Brown, A.H. Khan, S.R. Cherry, R.M. Leahy, T. Nichols, D.J. Smith, "Statistical Analysis of Multiplex Brain Gene Expression Images". Neurochem. Res., 27 (10): 1113-1121 2002. abstract

  7. V.M. Brown, A. Ossadtchi, A.H. Khan, S. Yee, G. Lacan, W.P. Melega, S.R. Cherry, R.M. Leahy, D.J. Smith, "Multiplex three dimensional brain gene expression mapping in a mouse model of Parkinson's disease", Genome Res 12 (6): 868-884 Jun 2002. pdf

  8. T.A. Leil, A. Ossadtchi, J. Cortes, R.M. Leahy, D.J. Smith, "Finding new candidate genes for learning and memory". Journal for Neuroscience Research, 68(2):127-137 Apr 15 2002. link

  9. V.M. Brown, A. Ossadtchi, S.S. Gambhir, S.R. Cherry, R.M. Leahy, D.J. Smith, "Gene expression tomography". Physiol. Genomics 8 (2) 159-167 Feb 28 2002. pdf

  10. V.M. Brown, A. Ossadtchi, A.H. Khan, S.R. Cherry, R.M. Leahy, D.J. Smith, "High throughput imaging of brain gene expression". Genome Res. 12: 244-254, 2002. pdf
  11. Z. Zhou, C. Synolakis, R. Leahy, and S. Song, "Calculation of 3D internal displacement fields from 3D x-ray computer tomographic-images", P Roy. Soc. Lond A Mat. 449(1937):537-554 Jun 8 1995.

  12. S. Song, R.M. Leahy, D. Boyd, B. Brundage and S. Napel, "Determining cardiac velocity fields and intraventricular pressure distribution from a sequence of ultrafast CT cardiac images", IEEE Trans. Medical Imaging, 13(2): 386-397 June 1994. pdf

  13. Z. Wu and R.M. Leahy, "An approximate method for evaluating the joint likelihood for GMRFs", IEEE Trans. Image Processing, Vol. 2, pp 520-523, 1993.

  14. M. Defrise, R. Clack and R.M. Leahy, "A note on Smith's reconstruction algorithm for cone beam tomography", IEEE Trans. Medical Imaging, Vol. 12, pp 622-623, 1993.

  15. X. Yan and R.M. Leahy, "Cone Beam Tomography With Circular, Elliptical And Spiral Orbits", Physics in Medicine and Biology, 37, PG 493 1992. PHYS MED BIOL 38(3):489-489 Mar 1993. abstract

  16. R.M. Leahy and B. Jeffs, "On the design of maximally sparse beamforming arrays", IEEE Trans. Antennas and Propagation,39(8): 1178-1187 Aug 1991. pdf

  17. S. Song and R.M. Leahy, "Computation of 3D velocity fields from 3D cine images of a beating heart", IEEE Trans. Med. Imag,10(3) 462-472 Sep 1991. pdf

  18. X. Yan and R.M. Leahy, "Derivation and analysis of a filtered backprojection algorithm for cone beam data", IEEE Trans. Med. Imag, Vol. MI10(3): 462-472 Dec 1991. pdf

  19. T. Hebert and R.M. Leahy, "A fast method for directly including attenuation in the EM algorithm", IEEE Trans. Nucl. Sci.,37(2): 754-758 Part 1 Apr 1990. pdf

  20. B. Jeffs, R.M. Leahy and M. Singh, "An evaluation of methods for neuromagnetic image reconstruction", IEEE Trans. on Biomed. Eng.,34(9): 713-723 Sep 1987.

  21. R.M. Leahy and C. Goutis, "Optimal feasible solutions for image restoration and reconstruction", IEEE trans. on Acoustics, Speech and Signal Processing, pp 1629-1642, Dec 1986.

Conference Publications:


  1. Darvas F., Chaudhari A. J., Leahy R. M., Effect of Skull Optical Properties on Hyperspectral Optical Tomography in Small Animals, Molecular Imaging, August 2005:4(3)5, Molecular Imaging, August 2005:4(3) (abstract)

  2. Chaudhari A. J., Darvas F., Cherry S. R., Leahy R. M. , Resolution studies in Bioluminescence and Fluorescence Optical Tomography using Hyperspectral Data Acquisition, Molecular Imaging and Biology, March 2005;7(6):125-126 (abstract)

  3. A. Chaudhari, F. Darvas, N. Serrano, D. J. Smith, S. R. Cherry, and R. M. Leahy, "Hyperspectral Optical Fluorescence Tomography for Small Animal Imaging", 2nd Annual Meeting of the Society of Molecular Imaging, Aug 2003. (abstract only)

  4. G. Zavattini, S. Vecchi, R.M. Leahy, S.J. Desmond, S.R. Cherry, "A Hyperspectral Fluorescence Imaging System for Biological Applications", in Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, 2003, Portland, OR, 2003. pdf

  5. G. Zavattini, S. Vecchi, R.M. Leahy, D.J. Smith, S.R. Cherry, "Multi-Fluoriphore Spectral Deconvolution With A Hyper-Spectral Imaging Apparatus", 2nd Annual Meeting of the Society of Molecular Imaging (abstract only) Aug 2003.

  6. J.G. Brankov, Yongyi Yang, R.M. Leahy, M.N. Wernick, "Multi-modality Tomographic Image Reconstruction Using Mesh Modeling", Biomedical Imaging, 2002 Proceedings. 2002 IEEE International Symposium, July 2002. pdf

  7. Alexei Ossadtchi, Arshad Khan, Richard M. Leahy, Desmond J. Smith, "Using Error-Correcting design to Improve cDNA Microarray Performance", Proc. GENSIPS (workshop on genomic processing), Raleigh, North Carolina, Oct, 2002. link

  8. S. Song, R.M. Leahy, D. Boyd, B. Brundage and S. Napel, "Determining cardiac velocity fields and intraventricular pressure distribution from a sequence of ultrafast CT cardiac images", IEEE Trans. Medical Imaging, Vol. 13, pp 386-397, June 1994. pdf

  9. S. Song and R.M. Leahy, "Computation of 3D velocity fields from 3D cine CT images of a human heart", IEEE Trans. Med. Imag, Vol. MI-10, pp 295-306, Sep 1991. pdf

Books and Book Chapters

  1. D. Pantazis , R.M. Leahy, "Imaging the Human Brain with Magnetoencephalography: Basics and Current Development", Handbook of Research on Informatics in Healthcare and Biomedicine, Ed. Athina Lazakidou, Idea Group Publishing, May 2006 (link)

  2. R. Leahy and R. Clackdoyle, Computed Tomography , In Handbook of Image Processing, Ed. A. Bovik, Feb, Academic Press, 2nd edition, pp 1155-1173, 2005.

  3. R. Leahy and R. Clackdoyle, Computed Tomography , In Handbook of Image Processing, pp 751-767, Ed. A. Bovik, Feb, Academic Press, Feb 2000.

  4. B. Timsari, J.M. Bouteiller, R. Leahy, M. Baudry, Registering 2-D Slice Data to 3-D Surface Atlases, In Computing the Brain: An Exemplary Approach to the Integration of Databases, Simulation, Visualization and the Internet, Eds. M. Arbib, J. Grethe, Academic Press, June 2000.

  5. R. Leahy, Tomography, Invited article in J. Wiley and Sons Encyclopedia of Electrical Engineering, Vol. 22, pp 280-289, Feb 1999.