EEG and epilepsy

This tutorial introduces some concepts that are specific to the management of EEG recordings in the Brainstorm environment. It also describes a standard pipeline for analyzing epilepsy recordings. It is based on clinical case from the Epilepsy Centre, at the University Hospital Freiburg, Germany. The EEG data was recorded at 1024Hz, using a Neurofile NT digital video-EEG system with 128 channels. The anonymized dataset can be downloaded directly from the Brainstorm download page.

The case from this tutorial is also published in this article: Dümpelmann M, Ball T, Schulze-Bonhage A
LORETA allows reliable distributed source reconstruction based on subdural strip and grid recordings, Hum Brain Mapp. 2012

License

This tutorial dataset (EEG and MRI data) remains proprietary of the Epilepsy Centre, University Hospital Freiburg, Germany. Its use and transfer outside the Brainstorm tutorial, e.g. for research purposes, is prohibited without written consent from the Epilepsy Centre in Freiburg. For questions please contact A. Schulze-Bonhage, MD, PhD: andreas.schulze-bonhage@uniklinik-freiburg.de

Presentation of the clinical case

The EEG data was recorded at 1024Hz, using a Neurofile NT digital video-EEG system with 128 channels and a 16-bit A/D converter. The signal was filtered in the recording system with a high-pass filter with a time constant of 1 second and a low-pass filter with a cutoff frequency of 344 Hz. The spikes were visually identified and averaged with the ASA package. The spike average showed prominent peaks in the grid contacts G_A2-4, G_B2-5, G_C1-3.

Type of epilepsy, supposed location, clinical conclusions, etc.

Download and installation

Import the anatomy

Without the individual MRI

If you do not have access to an individual MR scan of the subject (or if its quality is too low to be processed with FreeSurfer), but if you have digitized the head shape of the subject using a tracking system, you have an alternative: deform one of the Brainstorm templates (Colin27 or ICBM152) to match the shape of the subject's head.
For more information, read the following tutorial: Warping default anatomy

Access the recordings

anatomy.gif

Mark and review spikes

Source analysis

Moving dipoles

Illustrate John/Beth's tools for calculating and displaying dipoles.

Tools to be developed for this tutorial

SL_MNE_tutorial_patient.jpg

Tutorials/EpilepsyOld (last edited 2014-01-08 16:59:46 by agrippa)