Hi Fracois,
I'm following up on the discussion for source reconstruction of EEG data in stroke subjects. Following your recommendation, Christian and I created a modified surface and removed lesion scout to eliminate potential sources of neural activities originating from the peri-lesion surface. Apparently, this seems to be working fine for removing the lesion; however, when used for creating head models, the openMEG did not show any differences between reconstructed source fields before and after lesion removal. We think this might be due to 2 potential reasons: 1) openMEG still continues to use the intact brain surface for modeling, or 2) it somehow automatically recreates vertices for damaged brain areas and does the modeling similar to the original surface reconstruction. We would appreciate any input you may have to help us do source modeling correctly on the stroke data. I've uploaded two sample figures for the lead fields calculated using openMEG before and after lesion surface removal.
Best,
Roozbeh