= Digimouse: PET and Optical Simulations =
 . [[Digimouse|Overview]] | [[Digimouse_Data_Acquisition|Data Acquisition]] | [[Digimouse_Registration|Registration]] | [[Digimouse_Creation_of_Atlas|Creation of Atlas]] | '''Simulations''' | [[Digimouse_Download|Download]]

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||<width="100px" style="border:none; "><<EmbedObject(atlas_rendering_72x164.swf,width=72px,height=164px,play=true, loop=true)>> ||<style="border:none;">Our mouse atlas can be used to generate simulation images for PET and optical reconstructions. Here, we provide the Linear Attenuation Coefficients which were computed using the Mass Attenuation Coefficients of corresponding materials [[http://physics.nist.gov/PhysRefData/XrayMassCoef/cover.html|(Hubbell and Seltzer, 1996)]] that are assigned to the tissues in the atlas image          to create an attenuation coefficient image for PET simulation. <<BR>><<BR>> ||




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||<tablewidth="93%"62%>'''Tissue type''' ||<20%>'''Type of material''' ||<18%>'''LAC(cm^-1^)''' ||
||air ||Air ||1.04E-04 ||
||background ||Adipose tissue ||0.0913 ||
||skeleton ||bone cortical ||0.1717 ||
||eye ||Eye lens ||0.1012 ||
||medulla, olfactory bulbs, heart, lachrymal glands,              bladder wall, stomach, spleen, pancreas, liver, kindeys, adrenal glands,              skin ||Soft tissue ||0.1008 ||
||cerebellum, external cerebrum, striatum, rest of              the brain ||Brain ||0.0994 ||
||testes ||Testis ||0.0993 ||
||masseter muscles ||Muscle ||0.0999 ||
||lungs ||Lung tissue ||0.0999 ||
||bladder content ||Water ||0.0960 ||
||tumors ||Soft tissue ||0.1008 ||




'''''Figure:'''          Linear Attenuation Coefficients that are assigned to the tissues in the          atlas image to create an attenuation coefficient image for PET simulation''

For optical simulations scattering and absorption coefficients are computed          using the optical properties reported in

 * Alexandrakis, G., Rannou, F. R., and Chatziioannou, A. F. (2005). __Tomographic          bioluminescence imaging by use of a combined optical-pet (opet) system:          A computer simulation feasibility study__, Phys. Med. Biol., 50:4225–4241. http://dx.doi.org/10.1088/0031-9155/50/17/021 <<BR>><<BR>><<BR>>