BrainSuite is a magnetic resonance (MR) image analysis tool designed for identifying tissue types and surfaces in MR images of the human head.
BrainSuite was specifically designed to guide its users through the process of cortical surface extraction. We have written the software to require minimal user interaction and with the goal of completing the entire process of extracting a topologically spherical cortical surface from a raw MR volume within several minutes on a modern workstation. The individual components of BrainSuite may also be used for soft tissue, skull and scalp segmentation and for surface analysis and visualization. BrainSuite was written in Microsoft Visual C++ using the Microsoft Foundation Classes for its graphical user interface and the OpenGL library for rendering. BrainSuite runs under the Windows 2000 and Windows XP Professional operating systems.
BrainSuite has been written to be compatible with our ?BrainStorm Software package for the analysis of MEG and EEG data. Cortical surfaces extracted using BrainSuite can be used for part of a cortically constrained minimum norm imaging; brain, skull and scalp surfaces can be used to solve forward calculations using BEM or FEM functions in BrainStorm. BrainStorm also includes utilities to downsample surface tessellations and build FEM meshes from segmented volumes and surfaces.
BrainSuite was written by Dr. David W. Shattuck and is produced and distributed as a collaborative project between the Laboratory of Neuro Imaging at the University of California Los Angeles (Director: Dr. Arthur W. Toga) and the ?Biomedical Imaging Research Group at the University of Southern California (Director: Dr. Richard M. Leahy). The work is supported by grants from the National Institute of Biomedical Imaging and Bioengineering (R01 EB002010, PI: R.M. Leahy) and from the National Center for Research Resources (P41 RR013642, PI: A.W. Toga).
Contributors to the development of the methods embodied in this software include: David Shattuck, Anand Joshi, Belma Dogdas, Stephanie Sandor-Leahy, Bijan Timsari, Paul Thompson and Richard M. Leahy.
BrainSuite features include:
- Sophisticated visualization tools, such as MRI visualization in 3 orthogonal views (either seperately or in 3D view), and overlayed surface visualization of cortex, skull, and scalp
- Cortical surface extraction, using a multi-stage user friendly approach. Tools include brain surface extraction, bias field correction, voxel classification, cerebellum removal, and surface generation
- Topological correction of cortical surfaces, which uses a graph-based approach to remove topological defects (handles and holes) and ensure a tessellation with spherical topology
- Parameterization of generated cortical surfaces, minimizing a harmonic energy functional in the p-norm
- Skull and scalp surface extraction