Digimouse: PET and Optical Simulations
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Current configuration does not allow embedding of the file atlas_rendering_72x164.swf because of its mimetype application/x-shockwave-flash.: atlas_rendering_72x164.swf |
Our mouse atlas can be used to generate simulation images for PET and optical reconstructions. Here, we provide the Linear Attenuation Coefficients which were computed using the Mass Attenuation Coefficients of corresponding materials (Hubbell and Seltzer, 1996) that are assigned to the tissues in the atlas image to create an attenuation coefficient image for PET simulation. |
Tissue type |
Type of material |
LAC(cm-1) |
air |
Air |
1.04E-04 |
background |
Adipose tissue |
0.0913 |
skeleton |
bone cortical |
0.1717 |
eye |
Eye lens |
0.1012 |
medulla, olfactory bulbs, heart, lachrymal glands, bladder wall, stomach, spleen, pancreas, liver, kindeys, adrenal glands, skin |
Soft tissue |
0.1008 |
cerebellum, external cerebrum, striatum, rest of the brain |
Brain |
0.0994 |
testes |
Testis |
0.0993 |
masseter muscles |
Muscle |
0.0999 |
lungs |
Lung tissue |
0.0999 |
bladder content |
Water |
0.0960 |
tumors |
Soft tissue |
0.1008 |
Figure: Linear Attenuation Coefficients that are assigned to the tissues in the atlas image to create an attenuation coefficient image for PET simulation
For optical simulations scattering and absorption coefficients are computed using the optical properties reported in
Alexandrakis, G., Rannou, F. R., and Chatziioannou, A. F. (2005). Tomographic bioluminescence imaging by use of a combined optical-pet (opet) system: A computer simulation feasibility study, Phys. Med. Biol., 50:4225–4241. http://dx.doi.org/10.1088/0031-9155/50/17/021