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Revision 1 as of 2017-10-10 11:19:50
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SEEG epileptogencity maps

Authors: Francois Tadel, Olivier David.

This tutorial introduces some concepts that are specific to the management of SEEG recordings in the Brainstorm environment, and explains how to compute maps of epileptogenicity from ictal recordings. It is based on a clinical case from the Grenoble University Hospital, France.

Note that the operations used here are not detailed, the goal of this tutorial is not to introduce Brainstorm to new users. For in-depth explanations of the interface and theoretical foundations, please refer to the introduction tutorials.

Contents

  1. License
  2. Reference
  3. Download

License

This tutorial dataset (EEG and MRI data) remains property of the Grenoble University Hospital, France. Its use and transfer outside the ImaGIN tutorial, e.g. for research purposes, is prohibited without written consent. For questions, please contact Olivier David, PhD (olivier.david@grenoble-univ-alpes.fr).

Reference

The acquisition methodology is described in the following articles:

David O, Blauwblomme T, Job AS, Chabardès S, Hoffmann D, Minotti L, Kahane P
Imaging the seizure onset zone with stereo-electroencephalography
Brain. 2011 Oct;134(10):2898-911
https://academic.oup.com/brain/article/134/10/2898/323878

Lamarche F, Job AS, Deman P, Bhattacharjee M, Hoffmann D, Gallazzini-Crépin C, Bouvard S, Minotti L, Kahane P, David O
Correlation of FDG-PET hypometabolism and SEEG epileptogenicity mapping in patients with drug-resistant focal epilepsy
Epilepsia. 2016 Dec; 57(12):2045–2055
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214566/

Download

How to get the example dataset:

  • Download zip: https://gin11-git.ujf-grenoble.fr/ftract_dev/ImaGIN_datasets/tree/master/tutorial_epimap

  • Unzip on your computer, rename to "tutorial_epimap"

Files included in this package:

  • anat/MRI/3DT1*_deface.nii: Subject MRI before and after implantation, de-identified with FreeSurfer's mri_deface

  • anat/MRI/brainvisa: Cortical surface extracted with BrainVISA 4.5
  • anat/implantation/*.txt: Positions of the sEEG contacts in various formats (MNI coordinates or patient coordinates)
  • seeg/SZ*.TRC: Seizure recordings in Micromed format, one seizure per file
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